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BOSENTAN MONOHYDRATE
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DeCS
Descriptor
English
:
Bosentan
Descriptor
Spanish
:
Bosentán
Descriptor
Portuguese
:
Bosentana
Synonyms
English
:
4-t-Butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
Bosentan Anhydrous
Bosentan Monohydrate
Ro 47 0203
Ro 47-0203
Ro 470203
Ro-47-0203
Tracleer
Tree Number:
D02.065.884.135
D02.886.590.700.143
D03.383.742.060
Definition
English
:
A sulfonamide and pyrimidine derivative that acts as a dual endothelin receptor antagonist used to manage
PULMONARY HYPERTENSION
and SYSTEMIC
SCLEROSIS.
Pharmacological Action:
Antihypertensive Agents
Endothelin Receptor Antagonists
History Note
English
:
2019 (1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57600
Unique Identifier:
D000077300
Occurrence in VHL
:
Similar:
DeCS